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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIM1 All Species: 9.09
Human Site: S74 Identified Species: 25
UniProt: P11309 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11309 NP_002639.1 404 45412 S74 R H S P G S G S C G S S S G H
Chimpanzee Pan troglodytes XP_528972 440 46715 L96 P V S L L S T L A P P S P G S
Rhesus Macaque Macaca mulatta XP_001113117 663 74766 S333 R H S P G S G S C C S S S G H
Dog Lupus familis XP_548990 409 43442 S72 P S T L A P P S P G S P A S L
Cat Felis silvestris
Mouse Mus musculus P06803 397 44523 S72 L R R R C C S S R H R R R T D
Rat Rattus norvegicus P26794 313 35612 L34 P G K E K E P L E S Q Y Q V G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515486 364 41347 M73 X X X X F F V M S S F D Q R Y
Chicken Gallus gallus
Frog Xenopus laevis Q91822 323 36946 S44 E K V Y Q V G S V V A S G G F
Zebra Danio Brachydanio rerio Q9YHZ5 310 35169 T31 E H F E K Q Y T M G N L L G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.1 58.6 46.2 N.A. 85.8 75.2 N.A. 48 N.A. 51.4 37.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 57.9 59.8 57.4 N.A. 88.6 76.7 N.A. 61.1 N.A. 65 51.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 26.6 93.3 20 N.A. 6.6 0 N.A. 0 N.A. 26.6 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 93.3 33.3 N.A. 6.6 0 N.A. 6.6 N.A. 33.3 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 12 0 0 0 12 0 12 0 12 0 0 % A
% Cys: 0 0 0 0 12 12 0 0 23 12 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 12 % D
% Glu: 23 0 0 23 0 12 0 0 12 0 0 0 0 0 0 % E
% Phe: 0 0 12 0 12 12 0 0 0 0 12 0 0 0 12 % F
% Gly: 0 12 0 0 23 0 34 0 0 34 0 0 12 56 12 % G
% His: 0 34 0 0 0 0 0 0 0 12 0 0 0 0 23 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 12 12 0 23 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 12 0 0 23 12 0 0 23 0 0 0 12 12 0 12 % L
% Met: 0 0 0 0 0 0 0 12 12 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % N
% Pro: 34 0 0 23 0 12 23 0 12 12 12 12 12 0 0 % P
% Gln: 0 0 0 0 12 12 0 0 0 0 12 0 23 0 0 % Q
% Arg: 23 12 12 12 0 0 0 0 12 0 12 12 12 12 0 % R
% Ser: 0 12 34 0 0 34 12 56 12 23 34 45 23 12 23 % S
% Thr: 0 0 12 0 0 0 12 12 0 0 0 0 0 12 0 % T
% Val: 0 12 12 0 0 12 12 0 12 12 0 0 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 0 0 12 0 0 0 0 12 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _